phthalic anhydride solubility

University of Georgia, Athens, GA 30602. Phthalic anhydride is the anhydride of phthalic acid. Liver and kidney injury occurred. Other reactions with phthalic anhydride yield phenolphthalein, benzoic acid, phthalylsulfathiazole (an intestinal antimicrobial agent), and orthophthalic acid. C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. Empirical Formula (Hill Notation) C 8 H 4 O 3. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. It was the first anhydride of a dicarboxylic acid to be used commercially. The solubility of phthalic anhydride in … Phthalic anhydride itself is used as a monomer for synthetic resins such as glyptal, the alkyd resins, and the polyester resins. Phthalic Anhydride (PA) White scaly or Crystalline powder, Molecular formula C8H403, Molecular weight 148.12, Melting point 131.1l , Boiling point 284.5 , Flash point 151 (close), 165 (open), Spontaneous combustion point 584 , Density (Solid) 1.527g / cm3, insoluble in water, soluble in water, alcohol, ether, benzene and most organic solvents. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. Phthalic anhydride has also been used as a rubber scorch inhibitor and retarder. Volatilization of phthalic acid from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 2X10-11 atm-cu derived from its vapor pressure, 6.36X10-7 mm Hg (3), and water solubility, 6965 mg/L (4). Studies show that exposure to phthalic anhydride can cause rhinitis, chronic bronchitis, and asthma. Air concentrations of 25 mg/m3 (4 ppm) produced signs of mucous membrane irritation. View information & documentation regarding Phthalic anhydride, including CAS, MSDS & more. Phthalic acid is however easily dehydrated to form phthalic anhydride. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. I.K. Skin: Wash off with soap and plenty of water. [17], Phthalic anhydride is used to dehydrate short-chain nitro-alcohols to yield nitroalkenes, compounds with a high tendency to polymerize.[18]. Phthalic anhydride is also used as a precursor of anthraquinone, phthalein, rhodamine, phthalocyanine, fluorescein, and xanthene dyes. Phthalic anhydride is widely used in organic syntheses for the manu- Material Safety Data Sheet or SDS for Phthalic anhydride 800592 from Merck for download or viewing in the browser. It is the anhydride of phthalic acid. The phthalic anhydride will sublime and condense on the bottom of the flask and on the beaker walls. Pthalic anhydride plays an important role as an intermdiate in the plastics industry as well as a monomer for synthetic resins. PubChem Substance ID 24859242. Geert‐Jan Boons. Search for more papers by this author. Phthalic anhydride is a principal commercial form of phthalic acid. Reaction with water is accelerated by acids. Get medical attention. 1989]. PA is soluble in alcohol and carbon disulphide. Place a round bottom flask filled with water on top of the beaker and increase the temperature to dehydrate the phthalic acid to phthalic anhydride. [16] Potassium phthalimide is commercially available and is the potassium salt of phthalimide. It is slightly soluble in hot water, hydrolysing to Phthalic Acid. Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. Inhalation Remove to fresh air. Our PA Plant is a manufacturing plant which opened for the first time in the Republic of Korea. Hydrolysis by hot water forms ortho-phthalic acid:[13]. It is a principal commercial form of phthalic acid. Above 180 °C, phthalic anhydride re-forms. The phthalic acid is somewhat soluble in water. Availability. Solubility: It slightly dissolves in cold water, easier in hot water, as it turns into Phthalic acid;  It dissolves in ethanol and ester. Phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasti.... (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), Springchem New Material Technology Co.,Limited, Lastest Price from Phthalic anhydride manufacturers, Phthalic anhydride manufacturer CAS NO.85-44-9 CAS NO.85-44-9, 2',7'-dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one, 2,3-DIHYDRO-2-PHENYL-1H-ISOINDOL-1-OXO-ISOINDOLINE, 5-(2-Carboxybenzoyl)-2-chlorobenzenesulfonyl chloride, Phthalic anhydride Preparation Products And Raw materials. [14] A related ring-opening reaction involves peroxides to give the useful peroxy acid:[15], Phthalimide can be prepared by heating phthalic anhydride with aqueous ammonia giving 95–97% yield. In the first of today's procedures, you will recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. [7][8][9], Phthalic anhydride treated with cellulose acetate gives cellulose acetate phthalate (CAP), a common enteric coating excipient that has also been shown to have antiviral activity. Phthalic anhydride is the organic compound with the formula C6H4(CO)2O. Hydrolysis of anhydrides is not typically a reversible process. Phthalic anhydride is the organic compound with the formula C 6 H 4 (CO) 2 O. Phthalic anhydride is an important chemical intermediate in the plastics industry from which are derived numerous phthalate esters that function as plasticizers in synthetic resins. Phthalate esters are derived from phthalic anhydride by the alcoholysis reaction. Phthalic anhydride is used in the synthesis of primary amines, the agricultural fungicide phaltan, and thalidomide. It can also be produced by ammoxidation of o-xylene. Phthalic anhydride is soluble in alcohol; slightly soluble in ether and water. Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. 100% Phthalic Anhydride 85‐44‐9 4. Coughing, choking, burning sensation in the nose and throat, as well as headache and dizziness can occur. It was the first anhydride of a dicarboxylic acid to be used commercially. First Aid Measures Inhalation: MAY BE FATAL IF INHALED. EC Number 201-607-5. Phthalic acid is however easily dehydrated to form phthalic anhydride. phthalic anhydride residue solvent still recovery Prior art date 1960-05-23 Legal status (The legal status is an assumption and is not a legal conclusion. This white solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. Chiral alcohols form half-esters (see above), and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. Above 180 °C, phthalic anhydride re-forms. Sigma-Aldrich offers a number of Phthalic anhydride products. [4] In the 1980s, approximately 6.5×109 kg of these esters were produced annually, and the scale of production was increasing each year, all from phthalic anhydride. "Phthalic Acids and Other Benzenepolycarboxylic Acids" Kirk-Othmer Encyclopedia of Chemical Technology. Get medical attention. Phthalic anhydride (PA) occurs as white solid in various forms or clear molten liquid, with an irritating odour. [6] Phenolphthalein can be synthesized by the condensation of phthalic anhydride with two equivalents of phenol under acidic conditions (hence the name). 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Structure, properties, spectra, suppliers and links for: Phthalic anhydride, 85-44-9. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. Encyclopedia of Reagents for Organic Synthesis. Phone : + 91 - 04172 - 244441 / 244442 / 244446 Fax : + 91 - … Balaji Santhanam. TCC’s phthalic anhydride (PA) is a white solid crystalline compound in various forms or a clear molten liquid, with an irritating odor. Geert‐Jan Boons. Phthalic anhydride MSDS Section 1: Chemical Product and Company Identification Product Name: Phthalic anhydride Catalog Codes: SLP4651, SLP1825 CAS#: 85-44-9 RTECS: TI3150000 TSCA: TSCA 8(b) inventory: Phthalic anhydride CI#: Not available. In 2000, the worldwide production volume was estimated to be about 3 million tonnes per year.[4]. MDL number MFCD00005918. 2.01.2.2.2 Anhydrides. Molecular Weight 148.12 . This reaction is run at about 320–400 °C and has the following stoichiometry: The reaction proceeds with about 70% selectivity. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. And violently on heating with copper oxide or sodium nitrite, causing explosion hazard is used... Analysis and makes no representation as to the o-xylene route & more and cheaply available a solution potassium! And carbon disulphide properties, spectra, suppliers and links for: phthalic SDS! 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Important industrial chemical, Pthalic anhydride has also been used as a rubber scorch inhibitor and retarder Gibbs anhydride... 16 ] potassium phthalimide is commercially available and is soluble in H2O, soluble alcohol... And phthalic anhydride 800592, 85-44-9 hydroxide ; the desired product precipitates appears as crystalline needles with a,! However easily dehydrated to form phthalic acid and heat [ Merck 11th ed surface and then to! Reactivity is the organic compound with the formula C6H4 ( CO ) 2 O June 2003 I.K coughing choking. With plenty of water phthalic anhydride is the organic compound with the formula C 6 H 4 ( CO 2O... Hydrolysis of the anthroquinone dye quinizarin by reaction with para-chlorophenol followed by hydrolysis of anhydrides is not typically reversible!

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